MATERNAL DIABETES INDUCES CONGENITAL HEART DEFECTS IN MICE BY ALTERING THE EXPRESSION OF GENES INVOLVED IN CARDIOVASCULAR DEVELOPMENT

Maternal diabetes induces congenital heart defects in mice by altering the expression of genes involved in cardiovascular development

Abstract Background Congenital heart defects are frequently observed in infants of diabetic mothers, but the molecular basis of the defects remains obscure.Thus, the present study was performed to gain some insights into the molecular pathogenesis of maternal diabetes-induced congenital heart defects in mice.Methods and results We analyzed the morp

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Ulnar Collateral Ligament Repair With Suture Bridge Augmentation

The gold standard for management of elbow ulnar collateral ligament (UCL) injuries in elite athletes is reconstruction of the UCL with a tendon graft.Over the past several years, UCL repair for acute tears, as well Nutcracker as partial tears, in young athletes has gained increasing popularity, with studies reporting good outcomes and high rates of

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Chemotherapy-induced isolated right pan-retinal atrophy

INTRODUCTION Topically applied Birthing aids ocular medications could be sufficiently absorbed to inflict untoward systemic consequences.1-4 Timolol, a non-selective beta blocker is capable of eliciting severe asthmatic attacks in susceptible individuals.Timolol absorption is via nasal mucosa to systemic circulation.On another hand, systemically ad

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A Potentially Practicable Halotolerant Yeast Meyerozyma guilliermondii A4 for Decolorizing and Detoxifying Azo Dyes and Its Possible Halotolerance Mechanisms

In this study, a halotolerant yeast that is capable of efficiently decolorizing and detoxifying azo dyes was isolated, identified and characterized for coping with the treatment of azo-dye-containing wastewaters.A characterization of the yeast, CO-Q10 including the optimization of its metabolism and growth conditions, its detoxification effectivene

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